PRECLINICAL DRUG TESTING
The Bio-Imaging Lab provides extensive imaging service facilitating preclinical drug testing's and definition of early image-based biomarkers for CNS diseases. By employing state-of-art, in vivo imaging techniques including magnetic resonance imaging, magnetic resonance spectroscopy and bioluminescence imaging an in situ and quantative analysis of drug binding, efficacy and mechanism of action are generated.
Our research has created a continuous flow of MRI based (1) early disease markers and (2) markers for disease progression in rodent models of different neuropathologies including neurodegeneration and mood disorders. These markers form effective targets for assessing efficacy of new drugs. Our long standing experience with small animal imaging and various internationally extended collaborations have provided us broader access to supply of wider variety of animal disease models.
The staff from the different research lines play a key role in this preclinical research.
We are open to collaborations focusing on pre-clinical drug trials in small rodents or looking for new MRI/MRS biomarkers for diseases.
Contact person: Research & Innovation Manager: Dr. Pieter-Jan Guns
The Bio-Imaging Lab provides extensive imaging service facilitating preclinical drug testing's and definition of early image-based biomarkers for CNS diseases. By employing state-of-art, in vivo imaging techniques including magnetic resonance imaging, magnetic resonance spectroscopy and bioluminescence imaging an in situ and quantative analysis of drug binding, efficacy and mechanism of action are generated.
Our research has created a continuous flow of MRI based (1) early disease markers and (2) markers for disease progression in rodent models of different neuropathologies including neurodegeneration and mood disorders. These markers form effective targets for assessing efficacy of new drugs. Our long standing experience with small animal imaging and various internationally extended collaborations have provided us broader access to supply of wider variety of animal disease models.
The staff from the different research lines play a key role in this preclinical research.
We are open to collaborations focusing on pre-clinical drug trials in small rodents or looking for new MRI/MRS biomarkers for diseases.
Contact person: Research & Innovation Manager: Dr. Pieter-Jan Guns
