NMR MICROSCOPES
The lab is fully equipped and staffed for in vivo non-invasive small animal imaging, housing
The MR imagers allows IMAGING and SPECTROSCOPICAL investigation of specimens or living subjects of sizes ranging from 5 mm (imaging resolution = 30 micron) to 100 mm (imaging resolution = 90 micron).
Imaging facilitates visualizing the internal structure and function of the study object in a non-invasive and in vivo manner. Spectroscopy on the other hand allows, under the same circumstances, to monitor the biochemical signature of tissues.
A variety of RF coils for imaging and spectroscopical purposes are available either home-made or from Bruker.
We are equipped with animal monitoring devices (Pulse oxygenation, Temp., Resp. and ECG) (SA Instruments), work stations for image processing (MedX, IDL) and simultaneous EEG/MRI facilities with OSG software.
BIO-LUMINESCENCE IMAGING CAMERA
The Biospace Photon Imager is a iccd camera that allows for dynamic acquisition of bio-luminescence and fluorescence images.
Further information can be found on the Biospace website.
Fusion image of bio-luminescent signal in a mouse.
Endogeneous stem cells, locally transduced with firefly luciferase using lentiviral vectors.
Mouse provided by Prof. Baekelandt, Neurobiology and Gen Therapy Lab, KUL
Micro Computerized Tomography (Micro CT)
The lab also has access to micro-tomography instruments at the Micro CT Scan Research Group.
The in vivo micro-CT (Skyscan 1076) provides a high resolution low-dose X-ray scan in small laboratory animals to a maximal spatial resolution of up to 9 µm.
The in vitro micro-CT (Skyscan 1072) is a compact, desktop X-ray system for a non-invasive analysis of the inner structure of small specimen (< 1 cm3). At 80keV a resolution of 8 µm can be achieved.
Both scanners care capable of providing virtual cross-sections as well as 3D reconstructions.
The lab is fully equipped and staffed for in vivo non-invasive small animal imaging, housing
- 2 fully equiped 7T Pharmascans (Bruker BioSpin, Germany).
- 9.4T BioSpec horizontal bore Magnetic Resonance Imaging system (Bruker BioSpin, Germany).
- in vivo bio-luminescence and fluorescence camera (Biospace, France).
The MR imagers allows IMAGING and SPECTROSCOPICAL investigation of specimens or living subjects of sizes ranging from 5 mm (imaging resolution = 30 micron) to 100 mm (imaging resolution = 90 micron).
Imaging facilitates visualizing the internal structure and function of the study object in a non-invasive and in vivo manner. Spectroscopy on the other hand allows, under the same circumstances, to monitor the biochemical signature of tissues.
A variety of RF coils for imaging and spectroscopical purposes are available either home-made or from Bruker.
We are equipped with animal monitoring devices (Pulse oxygenation, Temp., Resp. and ECG) (SA Instruments), work stations for image processing (MedX, IDL) and simultaneous EEG/MRI facilities with OSG software.
BIO-LUMINESCENCE IMAGING CAMERA
The Biospace Photon Imager is a iccd camera that allows for dynamic acquisition of bio-luminescence and fluorescence images.
Further information can be found on the Biospace website.
Fusion image of bio-luminescent signal in a mouse.
Endogeneous stem cells, locally transduced with firefly luciferase using lentiviral vectors.
Mouse provided by Prof. Baekelandt, Neurobiology and Gen Therapy Lab, KUL
Micro Computerized Tomography (Micro CT)
The lab also has access to micro-tomography instruments at the Micro CT Scan Research Group.
The in vivo micro-CT (Skyscan 1076) provides a high resolution low-dose X-ray scan in small laboratory animals to a maximal spatial resolution of up to 9 µm.
The in vitro micro-CT (Skyscan 1072) is a compact, desktop X-ray system for a non-invasive analysis of the inner structure of small specimen (< 1 cm3). At 80keV a resolution of 8 µm can be achieved.
Both scanners care capable of providing virtual cross-sections as well as 3D reconstructions.
